Measuring the iron content of dopaminergic neurons in substantia nigra with MRI relaxometry

In Parkinson’s disease, the depletion of iron-rich dopaminergic neurons in nigrosome 1 of the substantia nigra precedes motor symptoms by two decades. Methods capable of monitoring this neuronal depletion, at an early disease stage, are needed for early diagnosis and treatment monitoring. Magnetic r...

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Detalles Bibliográficos
Autores principales: Brammerloh, Malte, Morawski, Markus, Friedrich, Isabel, Reinert, Tilo, Lange, Charlotte, Pelicon, Primož, Vavpetič, Primož, Jankuhn, Steffen, Jäger, Carsten, Alkemade, Anneke, Balesar, Rawien, Pine, Kerrin, Gavriilidis, Filippos, Trampel, Robert, Reimer, Enrico, Arendt, Thomas, Weiskopf, Nikolaus, Kirilina, Evgeniya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8363938/
https://www.ncbi.nlm.nih.gov/pubmed/34119638
http://dx.doi.org/10.1016/j.neuroimage.2021.118255

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