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PI3K-AKT, JAK2-STAT3 pathways and cell–cell contact regulate maspin subcellular localization
BACKGROUND: Maspin (SERPINB5) is a potential tumor suppressor gene with pleiotropic biological activities, including regulation of cell proliferation, death, adhesion, migration and gene expression. Several studies indicate that nuclear localization is essential for maspin tumor suppression activity...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364028/ https://www.ncbi.nlm.nih.gov/pubmed/34391444 http://dx.doi.org/10.1186/s12964-021-00758-3 |