PI3K-AKT, JAK2-STAT3 pathways and cell–cell contact regulate maspin subcellular localization

BACKGROUND: Maspin (SERPINB5) is a potential tumor suppressor gene with pleiotropic biological activities, including regulation of cell proliferation, death, adhesion, migration and gene expression. Several studies indicate that nuclear localization is essential for maspin tumor suppression activity...

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Detalles Bibliográficos
Autores principales: Longhi, M. T., Silva, L. E., Pereira, M., Magalhães, M., Reina, J., Vitorino, F. N. L., Gumbiner, B. M., da Cunha, J. P. C., Cella, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364028/
https://www.ncbi.nlm.nih.gov/pubmed/34391444
http://dx.doi.org/10.1186/s12964-021-00758-3

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