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Pathogenic roles and therapeutic potential of the CCL8–CCR8 axis in a murine model of IgG4-related sialadenitis

BACKGROUND: Our previous studies reveal that CCL18-CCR8 chemokine axis is upregulated in patients of immunoglobulin G4-related disease (IgG4-RD), suggesting that the CCL18–CCR8 axis is implicated in the etiology of IgG4-RD, although whether this axis has a potential as a therapeutic target remains u...

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Detalles Bibliográficos
Autores principales: Honda, Fumika, Tsuboi, Hiroto, Ono, Yuko, Abe, Saori, Takahashi, Hiroyuki, Ito, Kiyoaki, Yamada, Kazunori, Kawano, Mitsuhiro, Kondo, Yuya, Asano, Kenichi, Tanaka, Masato, Malissen, Marie, Malissen, Bernard, Matsumoto, Isao, Sumida, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364087/
https://www.ncbi.nlm.nih.gov/pubmed/34391459
http://dx.doi.org/10.1186/s13075-021-02597-6