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Dickkopf-related protein 3 alters aerobic glycolysis in pancreatic cancer BxPC-3 cells, promoting CD4(+) T-cell activation and function

BACKGROUND: To investigate the value of Dickkopf-related protein 3 (DKK3) on aerobic glycolysis in pancreatic cancer cells, where DKK3-overexpression is used to determine its effects on CD4(+) T cells. METHODS: The BxPC-3-DKK3 cell line was constructed, and peripheral blood mononuclear cell (PBMC) w...

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Detalles Bibliográficos
Autores principales: Guo, Qingqu, Chu, Yiming, Li, Hongbo, Shi, Dike, Lin, Lele, Lan, Weifeng, Wu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364117/
https://www.ncbi.nlm.nih.gov/pubmed/34391478
http://dx.doi.org/10.1186/s40001-021-00567-x

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