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Evaluation of radiophotoluminescent glass dosimeter response for therapeutic spot scanning proton beam: suggestion of linear energy transfer‐based correction
A radiophotoluminescent glass dosimeter (RGD) is used for a postal audit of a photon beam because of its various excellent characteristics. However, it has not been used for scanning proton beams because its response characteristics have not been verified. In this study, the response of RGD to scann...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364267/ https://www.ncbi.nlm.nih.gov/pubmed/34339583 http://dx.doi.org/10.1002/acm2.13378 |
Sumario: | A radiophotoluminescent glass dosimeter (RGD) is used for a postal audit of a photon beam because of its various excellent characteristics. However, it has not been used for scanning proton beams because its response characteristics have not been verified. In this study, the response of RGD to scanning protons was investigated to develop a dosimetry protocol using the linear energy transfer (LET)‐based correction factor. The responses of RGD to four maximum‐range‐energy‐pattern proton beams were verified by comparing it with ionization chamber (IC) dosimetry. The LET at each measurement depth was calculated via Monte Carlo (MC) simulation. The LET correction factor ([Formula: see text]) was the ratio between the uncorrected RGD dose ([Formula: see text]) and the IC dose at each measurement depth. [Formula: see text] can be represented as a function of LET using the following equation: [Formula: see text]. [Formula: see text] showed a linear under‐response with increasing LET, and the maximum dose difference between the IC dose and [Formula: see text] was 15.2% at an LET of 6.07 keV/μm. The LET‐based correction dose ([Formula: see text]) conformed within 3.6% of the IC dose. The mean dose difference (±SD) of [Formula: see text] and [Formula: see text] was –2.5 ± 6.9% and 0.0 ± 1.6%, respectively. To achieve accurate dose verification for scanning proton beams using RGD, we derived a linear regression equation based on LET. The results show that with appropriate LET correction, RGD can be used for dose verification of scanning proton beams. |
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