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Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1

Ewing sarcoma breakpoint region 1 (EWSR1) encodes a multifunctional protein that can cooperate with the transcription factor ERG to promote prostate cancer. The EWSR1 gene is also commonly involved in oncogenic gene rearrangements in Ewing sarcoma. Despite the cancer relevance of EWSR1, its regulati...

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Detalles Bibliográficos
Autores principales:	Nicholas, Taylor R, Metcalf, Stephanie A, Greulich, Benjamin M, Hollenhorst, Peter C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364332/ https://www.ncbi.nlm.nih.gov/pubmed/34409300 http://dx.doi.org/10.1093/narcan/zcab033

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