Elevated body fat increases amphetamine accumulation in brain: evidence from genetic and diet-induced forms of adiposity

Despite the high prevalence of obesity, little is known about its potential impact on the pharmacokinetics of psychotropic drugs. In the course of investigating the role of the microRNA system on neuronal signaling, we found that mice lacking the translin/trax microRNA-degrading enzyme display an ex...

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Detalles Bibliográficos
Autores principales: Fu, Xiuping, Shah, Aparna P., Keighron, Jacqueline, Mou, Ta-Chung M., Ladenheim, Bruce, Alt, Jesse, Fukudome, Daisuke, Niwa, Minae, Tamashiro, Kellie L., Tanda, Gianluigi, Sawa, Akira, Cadet, Jean-Lud, Rais, Rana, Baraban, Jay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364554/
https://www.ncbi.nlm.nih.gov/pubmed/34392304
http://dx.doi.org/10.1038/s41398-021-01547-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364554/
https://www.ncbi.nlm.nih.gov/pubmed/34392304
http://dx.doi.org/10.1038/s41398-021-01547-9

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