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Targeting the Membrane-Proximal C2-Set Domain of CD33 for Improved CD33-Directed Immunotherapy

There is increasing interest in targeting CD33 in malignant and non-malignant disorders. In acute myeloid leukemia, longer survival with the CD33 antibody-drug conjugate gemtuzumab ozogamicin (GO) validates this strategy. Still, GO benefits only some patients, prompting efforts to develop more poten...

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Detalles Bibliográficos
Autores principales:	Godwin, Colin D., Laszlo, George S., Fiorenza, Salvatore, Garling, Eliotte E., Phi, Tinh-Doan, Bates, Olivia M., Correnti, Colin E., Hoffstrom, Benjamin G., Lunn, Margaret C., Humbert, Olivier, Kiem, Hans-Peter, Turtle, Cameron J., Walter, Roland B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364569/ https://www.ncbi.nlm.nih.gov/pubmed/33589747 http://dx.doi.org/10.1038/s41375-021-01160-1

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