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HOTAIR promotes gefitinib resistance through modification of EZH2 and silencing p16 and p21 in non-small cell lung cancer

The long non-coding RNA Hox transcript antisense intergenic RNA (HOTAIR) plays a critical role in tumorigenesis as well as drug resistance in various cancers. However, the molecular mechanism by which HOTAIR induces gefitinib resistance in non-small cell lung cancer is to date unclear. In the presen...

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Detalles Bibliográficos
Autores principales: Li, Weiting, Li, Yongwen, Zhang, Hongbing, Liu, Minghui, Gong, Hao, Yuan, Yin, Shi, Ruifeng, Zhang, Zihe, Liu, Chao, Chen, Chen, Liu, Hongyu, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364642/
https://www.ncbi.nlm.nih.gov/pubmed/34405017
http://dx.doi.org/10.7150/jca.56093