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Safety, tolerability, pharmacokinetics and pharmacodynamics of single oral doses of BI 187004, an inhibitor of 11beta-hydroxysteroid dehydrogenase-1, in healthy male volunteers with overweight or obesity

BACKGROUND: The study characterizes safety, tolerability, pharmacokinetic and pharmacodynamic profiles of single rising doses of the 11beta-hydroxysteroid dehydrogenase-1 (11beta-HSD1) inhibitor BI 187004 in healthy men with overweight or obesity. METHODS: This was a randomized, double-blind, parall...

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Detalles Bibliográficos
Autores principales:	Bianzano, Susanna, Heise, Tim, Jungnik, Arvid, Schepers, Cornelia, Schölch, Corinna, Gräfe-Mody, Ulrike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364686/ https://www.ncbi.nlm.nih.gov/pubmed/34391480 http://dx.doi.org/10.1186/s40842-021-00130-x

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