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Downregulation of CCL22 and mutated NOTCH1 in tongue and mouth floor squamous cell carcinoma results in decreased Th2 cell recruitment and expression, predicting poor clinical outcome

OBJECTIVE: Tongue and mouth floor squamous cell carcinoma (T/MF SCC) exhibits a high rate of local recurrence and cervical lymph node metastasis. The effect of the tumor microenvironment on T/MF SCC remains unclear. MATERIALS AND METHODS: Transcriptome and somatic mutation data of patients with T/MF...

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Detalles Bibliográficos
Autores principales:	Li, Xuejie, Liu, Zheqi, Zhou, Wenkai, Liu, Xiaofang, Cao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364714/ https://www.ncbi.nlm.nih.gov/pubmed/34391381 http://dx.doi.org/10.1186/s12885-021-08671-1

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