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Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion
BACKGROUND: We assessed the long‐term clinical outcomes of an intermediate lesion (IL) according to the presence of a combined culprit lesion (CCL). HYPOTHESIS: Long‐term clinical outcomes of IL may be affected by the presence of a CCL. METHODS: Angiographic findings (n = 1096) and medical chart wer...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Periodicals, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364722/ https://www.ncbi.nlm.nih.gov/pubmed/34133033 http://dx.doi.org/10.1002/clc.23668 |
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author | Kim, Yong Kyun Jang, Chae Won Kwon, Soon Ho Kim, Jae Hoon Lerman, Amir Bae, Jang‐Ho |
author_facet | Kim, Yong Kyun Jang, Chae Won Kwon, Soon Ho Kim, Jae Hoon Lerman, Amir Bae, Jang‐Ho |
author_sort | Kim, Yong Kyun |
collection | PubMed |
description | BACKGROUND: We assessed the long‐term clinical outcomes of an intermediate lesion (IL) according to the presence of a combined culprit lesion (CCL). HYPOTHESIS: Long‐term clinical outcomes of IL may be affected by the presence of a CCL. METHODS: Angiographic findings (n = 1096) and medical chart were reviewed. Patients with IL were divided into two groups: IL without CCL group (n = 383, 64.5%) and IL with CCL group (n = 211, 35.5%). RESULTS: The major adverse cardiovascular events (MACE) in the IL with CCL group were significantly higher than those in the IL without CCL group (death: 12.3% vs. 7.0%, myocardial infarction: 3.3%vs. 0.5%, stroke: 6.6% vs. 2.6%, and revascularization [RVSC]: 25.1% vs. 7.6%) during a mean follow up period of 118.4 ± 5.5 months. IL related RVSC rate in the IL with CCL group was higher than that in the IL without CCL group (5.7% vs. 2.1%, p = 0.020). RVSC rate related to IL in total subjects was lower than that related to stented lesion (3.4% vs. 6.4%). The important predictors of total MACE in total subjects were the presence of CCL, IL percent diameter stenosis, hypertension, history of percutaneous coronary intervention, blood glucose and ejection fraction. The predictors of IL related RVSC were IL percent diameter stenosis and IL located in the right coronary artery. CONCLUSION: 10‐year clinical outcomes of an IL (especially IL without CCL) were better than those of stented lesions. This study suggests that the IL can be safely followed up in sites that do not have ability to assess functional study. |
format | Online Article Text |
id | pubmed-8364722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wiley Periodicals, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83647222021-08-23 Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion Kim, Yong Kyun Jang, Chae Won Kwon, Soon Ho Kim, Jae Hoon Lerman, Amir Bae, Jang‐Ho Clin Cardiol Clinical Investigations BACKGROUND: We assessed the long‐term clinical outcomes of an intermediate lesion (IL) according to the presence of a combined culprit lesion (CCL). HYPOTHESIS: Long‐term clinical outcomes of IL may be affected by the presence of a CCL. METHODS: Angiographic findings (n = 1096) and medical chart were reviewed. Patients with IL were divided into two groups: IL without CCL group (n = 383, 64.5%) and IL with CCL group (n = 211, 35.5%). RESULTS: The major adverse cardiovascular events (MACE) in the IL with CCL group were significantly higher than those in the IL without CCL group (death: 12.3% vs. 7.0%, myocardial infarction: 3.3%vs. 0.5%, stroke: 6.6% vs. 2.6%, and revascularization [RVSC]: 25.1% vs. 7.6%) during a mean follow up period of 118.4 ± 5.5 months. IL related RVSC rate in the IL with CCL group was higher than that in the IL without CCL group (5.7% vs. 2.1%, p = 0.020). RVSC rate related to IL in total subjects was lower than that related to stented lesion (3.4% vs. 6.4%). The important predictors of total MACE in total subjects were the presence of CCL, IL percent diameter stenosis, hypertension, history of percutaneous coronary intervention, blood glucose and ejection fraction. The predictors of IL related RVSC were IL percent diameter stenosis and IL located in the right coronary artery. CONCLUSION: 10‐year clinical outcomes of an IL (especially IL without CCL) were better than those of stented lesions. This study suggests that the IL can be safely followed up in sites that do not have ability to assess functional study. Wiley Periodicals, Inc. 2021-06-16 /pmc/articles/PMC8364722/ /pubmed/34133033 http://dx.doi.org/10.1002/clc.23668 Text en © 2021 The Authors. Clinical Cardiology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Investigations Kim, Yong Kyun Jang, Chae Won Kwon, Soon Ho Kim, Jae Hoon Lerman, Amir Bae, Jang‐Ho Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
title | Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
title_full | Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
title_fullStr | Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
title_full_unstemmed | Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
title_short | Ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
title_sort | ten‐year clinical outcomes in patients with intermediate coronary stenosis according to the combined culprit lesion |
topic | Clinical Investigations |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364722/ https://www.ncbi.nlm.nih.gov/pubmed/34133033 http://dx.doi.org/10.1002/clc.23668 |
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