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National trends in repair for type B aortic dissection

BACKGROUND: Thoracic endovascular aortic repair (TEVAR) first gained in popularity for repair of type B aortic dissections (TBADs) in the early 2000's. We aimed to describe patients undergoing open repair, TEVAR, and no repair and analyze factors associated with repair within 14 days of present...

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Autores principales: Weissler, E. Hope, Osazuwa‐Peters, Oyomoare L., Greiner, Melissa A., Hughes, G. Chad, Long, Chandler A., Vemulapalli, Sreekanth, Patel, Manesh R., Jones, W. Schuyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364733/
https://www.ncbi.nlm.nih.gov/pubmed/34173677
http://dx.doi.org/10.1002/clc.23672
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author Weissler, E. Hope
Osazuwa‐Peters, Oyomoare L.
Greiner, Melissa A.
Hughes, G. Chad
Long, Chandler A.
Vemulapalli, Sreekanth
Patel, Manesh R.
Jones, W. Schuyler
author_facet Weissler, E. Hope
Osazuwa‐Peters, Oyomoare L.
Greiner, Melissa A.
Hughes, G. Chad
Long, Chandler A.
Vemulapalli, Sreekanth
Patel, Manesh R.
Jones, W. Schuyler
author_sort Weissler, E. Hope
collection PubMed
description BACKGROUND: Thoracic endovascular aortic repair (TEVAR) first gained in popularity for repair of type B aortic dissections (TBADs) in the early 2000's. We aimed to describe patients undergoing open repair, TEVAR, and no repair and analyze factors associated with repair within 14 days of presentation in the contemporary era. METHODS: We used the MarketScan database to find patients with TBAD between 2014 and 2017. To assess factors associated with early repair, univariable, and multivariable log‐binomial regression were used. RESULTS: There were 2613 patients admitted with TBAD between 2014 and 2017 across the United States, of whom 38.4% underwent repair within 14 days of admission (25.3% open repair and 13.1% TEVAR). The incidence of repair within 14 days decreased over the study period (43% of the study cohort in 2014 to 26.4% in 2017) primarily due to a decrease in open repairs from 30.8% of patients in 2014 to 12.5% in 2017. In multivariable analysis, older age, Middle Atlantic location, diabetes mellitus, insulin use, antiplatelet use, and more recent year were associated with lower likelihood of early repair; male sex, peripheral vascular disease, and the presence of extremity ischemia, rupture, shock, and acidosis were associated with higher likelihood of repair. CONCLUSIONS: Overall, repair of TBAD within 14 days of presentation declined from 2014 to 2017, with a steady rate of TEVAR but declining rate of open repairs. Further investigation into provider‐ and hospital‐specific factors as they relate to likelihood of repair is needed.
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spelling pubmed-83647332021-08-23 National trends in repair for type B aortic dissection Weissler, E. Hope Osazuwa‐Peters, Oyomoare L. Greiner, Melissa A. Hughes, G. Chad Long, Chandler A. Vemulapalli, Sreekanth Patel, Manesh R. Jones, W. Schuyler Clin Cardiol Clinical Trial Result BACKGROUND: Thoracic endovascular aortic repair (TEVAR) first gained in popularity for repair of type B aortic dissections (TBADs) in the early 2000's. We aimed to describe patients undergoing open repair, TEVAR, and no repair and analyze factors associated with repair within 14 days of presentation in the contemporary era. METHODS: We used the MarketScan database to find patients with TBAD between 2014 and 2017. To assess factors associated with early repair, univariable, and multivariable log‐binomial regression were used. RESULTS: There were 2613 patients admitted with TBAD between 2014 and 2017 across the United States, of whom 38.4% underwent repair within 14 days of admission (25.3% open repair and 13.1% TEVAR). The incidence of repair within 14 days decreased over the study period (43% of the study cohort in 2014 to 26.4% in 2017) primarily due to a decrease in open repairs from 30.8% of patients in 2014 to 12.5% in 2017. In multivariable analysis, older age, Middle Atlantic location, diabetes mellitus, insulin use, antiplatelet use, and more recent year were associated with lower likelihood of early repair; male sex, peripheral vascular disease, and the presence of extremity ischemia, rupture, shock, and acidosis were associated with higher likelihood of repair. CONCLUSIONS: Overall, repair of TBAD within 14 days of presentation declined from 2014 to 2017, with a steady rate of TEVAR but declining rate of open repairs. Further investigation into provider‐ and hospital‐specific factors as they relate to likelihood of repair is needed. Wiley Periodicals, Inc. 2021-06-26 /pmc/articles/PMC8364733/ /pubmed/34173677 http://dx.doi.org/10.1002/clc.23672 Text en © 2021 The Authors. Clinical Cardiology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Trial Result
Weissler, E. Hope
Osazuwa‐Peters, Oyomoare L.
Greiner, Melissa A.
Hughes, G. Chad
Long, Chandler A.
Vemulapalli, Sreekanth
Patel, Manesh R.
Jones, W. Schuyler
National trends in repair for type B aortic dissection
title National trends in repair for type B aortic dissection
title_full National trends in repair for type B aortic dissection
title_fullStr National trends in repair for type B aortic dissection
title_full_unstemmed National trends in repair for type B aortic dissection
title_short National trends in repair for type B aortic dissection
title_sort national trends in repair for type b aortic dissection
topic Clinical Trial Result
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364733/
https://www.ncbi.nlm.nih.gov/pubmed/34173677
http://dx.doi.org/10.1002/clc.23672
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