Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study

We conducted a matched case–control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.

Detalles Bibliográficos
Autores principales: Oliveira, Carlos R, Massad, Christopher, Shapiro, Eugene D, Vazquez, Marietta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364756/
https://www.ncbi.nlm.nih.gov/pubmed/34409119
http://dx.doi.org/10.1093/ofid/ofab142
_version_ 1783738579558596608
author Oliveira, Carlos R
Massad, Christopher
Shapiro, Eugene D
Vazquez, Marietta
author_facet Oliveira, Carlos R
Massad, Christopher
Shapiro, Eugene D
Vazquez, Marietta
author_sort Oliveira, Carlos R
collection PubMed
description We conducted a matched case–control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.
format Online
Article
Text
id pubmed-8364756
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-83647562021-08-17 Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study Oliveira, Carlos R Massad, Christopher Shapiro, Eugene D Vazquez, Marietta Open Forum Infect Dis Brief Report We conducted a matched case–control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting. Oxford University Press 2021-04-17 /pmc/articles/PMC8364756/ /pubmed/34409119 http://dx.doi.org/10.1093/ofid/ofab142 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Oliveira, Carlos R
Massad, Christopher
Shapiro, Eugene D
Vazquez, Marietta
Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
title Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
title_full Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
title_fullStr Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
title_full_unstemmed Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
title_short Clinical Effectiveness of Lyme Vaccine: A Matched Case–Control Study
title_sort clinical effectiveness of lyme vaccine: a matched case–control study
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364756/
https://www.ncbi.nlm.nih.gov/pubmed/34409119
http://dx.doi.org/10.1093/ofid/ofab142
work_keys_str_mv AT oliveiracarlosr clinicaleffectivenessoflymevaccineamatchedcasecontrolstudy
AT massadchristopher clinicaleffectivenessoflymevaccineamatchedcasecontrolstudy
AT shapiroeugened clinicaleffectivenessoflymevaccineamatchedcasecontrolstudy
AT vazquezmarietta clinicaleffectivenessoflymevaccineamatchedcasecontrolstudy

Ejemplares similares