A Deep Dive into the Pathology of Gray Platelet Syndrome: New Insights on Immune Dysregulation

The gray platelet syndrome (GPS) is a rare platelet disorder, characterized by impaired alpha-granule biogenesis in megakaryocytes and platelets due to NBEAL2 mutations. Typical clinical features include macrothrombocytopenia, bleeding and elevated vitamin B12 levels, while bone marrow fibrosis and...

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Detalles Bibliográficos
Autores principales: Glembotsky, Ana C, De Luca, Geraldine, Heller, Paula G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364843/
https://www.ncbi.nlm.nih.gov/pubmed/34408521
http://dx.doi.org/10.2147/JBM.S270018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364843/
https://www.ncbi.nlm.nih.gov/pubmed/34408521
http://dx.doi.org/10.2147/JBM.S270018

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