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High-Loading Self-Assembling Peptide Nanoparticles as a Lipid-Free Carrier for Hydrophobic General Anesthetics

PURPOSE: Typical hydrophobic amino acids (HAAs) are important motifs for self-assembling peptides (SAPs), but they lead to low water-solubility or compact packing of peptides, limiting their capacity for encapsulating hydrophobic drugs. As an alternative, we designed a peptide GQY based on atypical...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Peng, Fei, Kang, Yi, Gong, Deying, Fan, Jing, Zhang, Wensheng, Qiu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364852/
https://www.ncbi.nlm.nih.gov/pubmed/34408412
http://dx.doi.org/10.2147/IJN.S315310