The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs

The generation of inducible pluripotent stem cells (iPSCs) is a revolutionary technique allowing production of pluripotent patient-specific cell lines used for disease modeling, drug screening, and cell therapy. Integrity of nuclear DNA (nDNA) is mandatory to allow iPSCs utilization, while quality c...

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Detalles Bibliográficos
Autores principales: Palombo, Flavia, Peron, Camille, Caporali, Leonardo, Iannielli, Angelo, Maresca, Alessandra, Di Meo, Ivano, Fiorini, Claudio, Segnali, Alice, Sciacca, Francesca L., Rizzo, Ambra, Levi, Sonia, Suomalainen, Anu, Prigione, Alessandro, Broccoli, Vania, Carelli, Valerio, Tiranti, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365099/
https://www.ncbi.nlm.nih.gov/pubmed/34329598
http://dx.doi.org/10.1016/j.stemcr.2021.06.016

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