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Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery

Objective: Investigate whether machine learning can predict pulmonary complications (PPCs) after emergency gastrointestinal surgery in patients with acute diffuse peritonitis. Methods: This is a secondary data analysis study. We use five machine learning algorithms (Logistic regression, DecisionTree...

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Autores principales: Xue, Qiong, Wen, Duan, Ji, Mu-Huo, Tong, Jianhua, Yang, Jian-Jun, Zhou, Cheng-Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365303/
https://www.ncbi.nlm.nih.gov/pubmed/34409047
http://dx.doi.org/10.3389/fmed.2021.655686
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author Xue, Qiong
Wen, Duan
Ji, Mu-Huo
Tong, Jianhua
Yang, Jian-Jun
Zhou, Cheng-Mao
author_facet Xue, Qiong
Wen, Duan
Ji, Mu-Huo
Tong, Jianhua
Yang, Jian-Jun
Zhou, Cheng-Mao
author_sort Xue, Qiong
collection PubMed
description Objective: Investigate whether machine learning can predict pulmonary complications (PPCs) after emergency gastrointestinal surgery in patients with acute diffuse peritonitis. Methods: This is a secondary data analysis study. We use five machine learning algorithms (Logistic regression, DecisionTree, GradientBoosting, Xgbc, and gbm) to predict postoperative pulmonary complications. Results: Nine hundred and twenty-six cases were included in this study; 187 cases (20.19%) had PPCs. The five most important variables for the postoperative weight were preoperative albumin, cholesterol on the 3rd day after surgery, albumin on the day of surgery, platelet count on the 1st day after surgery and cholesterol count on the 1st day after surgery for pulmonary complications. In the test group: the logistic regression model shows AUC = 0.808, accuracy = 0.824 and precision = 0.621; Decision tree shows AUC = 0.702, accuracy = 0.795 and precision = 0.486; The GradientBoosting model shows AUC = 0.788, accuracy = 0.827 and precision = 1.000; The Xgbc model shows AUC = 0.784, accuracy = 0.806 and precision = 0.583. The Gbm model shows AUC = 0.814, accuracy = 0.806 and precision = 0.750. Conclusion: Machine learning algorithms can predict patients' PPCs with acute diffuse peritonitis. Moreover, the results of the importance matrix for the Gbdt algorithm model show that albumin, cholesterol, age, and platelets are the main variables that account for the highest pulmonary complication weights.
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spelling pubmed-83653032021-08-17 Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery Xue, Qiong Wen, Duan Ji, Mu-Huo Tong, Jianhua Yang, Jian-Jun Zhou, Cheng-Mao Front Med (Lausanne) Medicine Objective: Investigate whether machine learning can predict pulmonary complications (PPCs) after emergency gastrointestinal surgery in patients with acute diffuse peritonitis. Methods: This is a secondary data analysis study. We use five machine learning algorithms (Logistic regression, DecisionTree, GradientBoosting, Xgbc, and gbm) to predict postoperative pulmonary complications. Results: Nine hundred and twenty-six cases were included in this study; 187 cases (20.19%) had PPCs. The five most important variables for the postoperative weight were preoperative albumin, cholesterol on the 3rd day after surgery, albumin on the day of surgery, platelet count on the 1st day after surgery and cholesterol count on the 1st day after surgery for pulmonary complications. In the test group: the logistic regression model shows AUC = 0.808, accuracy = 0.824 and precision = 0.621; Decision tree shows AUC = 0.702, accuracy = 0.795 and precision = 0.486; The GradientBoosting model shows AUC = 0.788, accuracy = 0.827 and precision = 1.000; The Xgbc model shows AUC = 0.784, accuracy = 0.806 and precision = 0.583. The Gbm model shows AUC = 0.814, accuracy = 0.806 and precision = 0.750. Conclusion: Machine learning algorithms can predict patients' PPCs with acute diffuse peritonitis. Moreover, the results of the importance matrix for the Gbdt algorithm model show that albumin, cholesterol, age, and platelets are the main variables that account for the highest pulmonary complication weights. Frontiers Media S.A. 2021-08-02 /pmc/articles/PMC8365303/ /pubmed/34409047 http://dx.doi.org/10.3389/fmed.2021.655686 Text en Copyright © 2021 Xue, Wen, Ji, Tong, Yang and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Xue, Qiong
Wen, Duan
Ji, Mu-Huo
Tong, Jianhua
Yang, Jian-Jun
Zhou, Cheng-Mao
Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery
title Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery
title_full Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery
title_fullStr Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery
title_full_unstemmed Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery
title_short Developing Machine Learning Algorithms to Predict Pulmonary Complications After Emergency Gastrointestinal Surgery
title_sort developing machine learning algorithms to predict pulmonary complications after emergency gastrointestinal surgery
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365303/
https://www.ncbi.nlm.nih.gov/pubmed/34409047
http://dx.doi.org/10.3389/fmed.2021.655686
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