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Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide
Children with autoimmune disorders are especially at risk of vaccine-preventable diseases due to their underlying disease and the immunosuppressive treatment often required for a long period. In addition, vaccine coverage remains too low in this vulnerable population. This can be explained by a fear...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365419/ https://www.ncbi.nlm.nih.gov/pubmed/34408752 http://dx.doi.org/10.3389/fimmu.2021.711637 |
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author | Blanchard-Rohner, Geraldine |
author_facet | Blanchard-Rohner, Geraldine |
author_sort | Blanchard-Rohner, Geraldine |
collection | PubMed |
description | Children with autoimmune disorders are especially at risk of vaccine-preventable diseases due to their underlying disease and the immunosuppressive treatment often required for a long period. In addition, vaccine coverage remains too low in this vulnerable population. This can be explained by a fear of possible adverse effects of vaccines under immunosuppression, but also a lack of data and clear recommendations, particularly with regard to vaccination with live vaccines. In this review, the latest literature and recommendations on vaccination in immunosuppressed children are discussed in detail, with the aim to provide a set of practical guidelines on vaccination for specialists caring for children suffering from different autoimmune disorders and treated with various immunosuppressive regimens. |
format | Online Article Text |
id | pubmed-8365419 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83654192021-08-17 Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide Blanchard-Rohner, Geraldine Front Immunol Immunology Children with autoimmune disorders are especially at risk of vaccine-preventable diseases due to their underlying disease and the immunosuppressive treatment often required for a long period. In addition, vaccine coverage remains too low in this vulnerable population. This can be explained by a fear of possible adverse effects of vaccines under immunosuppression, but also a lack of data and clear recommendations, particularly with regard to vaccination with live vaccines. In this review, the latest literature and recommendations on vaccination in immunosuppressed children are discussed in detail, with the aim to provide a set of practical guidelines on vaccination for specialists caring for children suffering from different autoimmune disorders and treated with various immunosuppressive regimens. Frontiers Media S.A. 2021-08-02 /pmc/articles/PMC8365419/ /pubmed/34408752 http://dx.doi.org/10.3389/fimmu.2021.711637 Text en Copyright © 2021 Blanchard-Rohner https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Blanchard-Rohner, Geraldine Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide |
title | Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide |
title_full | Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide |
title_fullStr | Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide |
title_full_unstemmed | Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide |
title_short | Vaccination in Children With Autoimmune Disorders and Treated With Various Immunosuppressive Regimens: A Comprehensive Review and Practical Guide |
title_sort | vaccination in children with autoimmune disorders and treated with various immunosuppressive regimens: a comprehensive review and practical guide |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365419/ https://www.ncbi.nlm.nih.gov/pubmed/34408752 http://dx.doi.org/10.3389/fimmu.2021.711637 |
work_keys_str_mv | AT blanchardrohnergeraldine vaccinationinchildrenwithautoimmunedisordersandtreatedwithvariousimmunosuppressiveregimensacomprehensivereviewandpracticalguide |