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A Convenient Chemoenzymatic Preparation of Chimeric Macrocyclic Peptide Antibiotics with Potent Activity against Gram-Negative Pathogens
[Image: see text] The continuing rise of antibiotic resistance, particularly among Gram-negative pathogens, threatens to undermine many aspects of modern medical practice. To address this threat, novel antibiotics that utilize unexploited bacterial targets are urgently needed. Over the past decade,...
Autores principales: | Wood, Thomas M., Slingerland, Cornelis J., Martin, Nathaniel I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365600/ https://www.ncbi.nlm.nih.gov/pubmed/34283589 http://dx.doi.org/10.1021/acs.jmedchem.1c00176 |
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