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A Convenient Chemoenzymatic Preparation of Chimeric Macrocyclic Peptide Antibiotics with Potent Activity against Gram-Negative Pathogens

[Image: see text] The continuing rise of antibiotic resistance, particularly among Gram-negative pathogens, threatens to undermine many aspects of modern medical practice. To address this threat, novel antibiotics that utilize unexploited bacterial targets are urgently needed. Over the past decade,...

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Detalles Bibliográficos
Autores principales: Wood, Thomas M., Slingerland, Cornelis J., Martin, Nathaniel I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365600/
https://www.ncbi.nlm.nih.gov/pubmed/34283589
http://dx.doi.org/10.1021/acs.jmedchem.1c00176

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