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Quantification of glycated IgG in CHO supernatants: A practical approach
Post‐translational, nonenzymatic glycation of monoclonal antibodies (mAbs) in the presence of reducing sugars (in bioprocesses) is a widely known phenomenon, which affects protein heterogeneity and potentially has an impact on quality, safety, and efficacy of the end product. Quantification of indiv...
Autores principales: | Lhota, Gabriele, Sissolak, Bernhard, Striedner, Gerald, Sommeregger, Wolfgang, Vorauer‐Uhl, Karola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365726/ https://www.ncbi.nlm.nih.gov/pubmed/33428326 http://dx.doi.org/10.1002/btpr.3124 |
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