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Quantification of glycated IgG in CHO supernatants: A practical approach

Post‐translational, nonenzymatic glycation of monoclonal antibodies (mAbs) in the presence of reducing sugars (in bioprocesses) is a widely known phenomenon, which affects protein heterogeneity and potentially has an impact on quality, safety, and efficacy of the end product. Quantification of indiv...

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Detalles Bibliográficos
Autores principales: Lhota, Gabriele, Sissolak, Bernhard, Striedner, Gerald, Sommeregger, Wolfgang, Vorauer‐Uhl, Karola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365726/
https://www.ncbi.nlm.nih.gov/pubmed/33428326
http://dx.doi.org/10.1002/btpr.3124

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