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Metformin attenuates silica-induced pulmonary fibrosis via AMPK signaling

BACKGROUND: Silicosis is one of the most common occupational pulmonary fibrosis caused by respirable silica-based particle exposure, with no ideal drugs at present. Metformin, a commonly used biguanide antidiabetic agent, could activate AMP-activated protein kinase (AMPK) to exert its pharmacologica...

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Detalles Bibliográficos
Autores principales:	Cheng, Demin, Xu, Qi, Wang, Yue, Li, Guanru, Sun, Wenqing, Ma, Dongyu, Zhou, Siyun, Liu, Yi, Han, Lei, Ni, Chunhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365894/ https://www.ncbi.nlm.nih.gov/pubmed/34399790 http://dx.doi.org/10.1186/s12967-021-03036-5

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