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Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

BACKGROUND: Failing of intrinsic chondrocyte repair after mechanical stress is known as one of the most important initiators of osteoarthritis. Nonetheless, insight into these early mechano-pathophysiological processes in age-related human articular cartilage is still lacking. Such insights are need...

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Detalles Bibliográficos
Autores principales: Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D., van der Wal, Robert J. P., Nelissen, Rob G. H. H., Mei, Hailiang, Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365911/
https://www.ncbi.nlm.nih.gov/pubmed/34399844
http://dx.doi.org/10.1186/s13075-021-02595-8