Cargando…

Characterizing DNA methylation signatures and their potential functional roles in Merkel cell carcinoma

BACKGROUND: Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with limited treatment possibilities. Merkel cell tumors display with neuroendocrine features and Merkel cell polyomavirus (MCPyV) infection in the majority (80%) of patients. Although loss of histone H3 lysine 27 trimethyl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gujar, Hemant, Mehta, Arjun, Li, Hong-Tao, Tsai, Yvonne C., Qiu, Xiangning, Weisenberger, Daniel J., Jasiulionis, Miriam Galvonas, In, Gino K., Liang, Gangning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365948/ https://www.ncbi.nlm.nih.gov/pubmed/34399838 http://dx.doi.org/10.1186/s13073-021-00946-3

Ejemplares similares

The Roles of Human DNA Methyltransferases and Their Isoforms in Shaping the Epigenome
por: Gujar, Hemant, et al.
Publicado: (2019)

Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients
por: Papaiz, Debora D’Angelo, et al.
Publicado: (2022)

A Novel DNA Methylation Signature as an Independent Prognostic Factor in Muscle-Invasive Bladder Cancer
por: Xu, Zhijie, et al.
Publicado: (2021)

Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy
por: Li, Hong-Tao, et al.
Publicado: (2022)

The Role of SIRT1 on DNA Damage Response and Epigenetic Alterations in Cancer
por: Alves-Fernandes, Débora Kristina, et al.
Publicado: (2019)

Characteristics of TIMP1, CD63, and β1-Integrin and the Functional Impact of Their Interaction in Cancer
por: Justo, Beatriz Laís, et al.
Publicado: (2021)

miRNAs and Melanoma: How Are They Connected?
por: da Cruz, Adriana Taveira, et al.
Publicado: (2012)

Editorial: The functions of extracellular vesicles in melanoma
por: García-Silva, Susana, et al.
Publicado: (2023)

Extracellular vesicles and melanoma: New perspectives on tumor microenvironment and metastasis
por: Benito-Martín, Alberto, et al.
Publicado: (2023)

Biomarkers as Key Contributors in Treating Malignant Melanoma Metastases
por: de Souza, Camila Ferreira, et al.
Publicado: (2012)

The Role of the BH4 Cofactor in Nitric Oxide Synthase Activity and Cancer Progression: Two Sides of the Same Coin
por: Gonçalves, Diego Assis, et al.
Publicado: (2021)

The Roles of miR-26, miR-29, and miR-203 in the Silencing of the Epigenetic Machinery during Melanocyte Transformation
por: Gasque Schoof, Cláudia Regina, et al.
Publicado: (2015)

Epigenetic Regulation in Sepsis, Role in Pathophysiology and Therapeutic Perspective
por: Falcão-Holanda, Renata Brito, et al.
Publicado: (2021)

Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray
por: Gujar, Hemant, et al.
Publicado: (2018)

Ras and Rac1, Frequently Mutated in Melanomas, Are Activated by Superoxide Anion, Modulate Dnmt1 Level and Are Causally Related to Melanocyte Malignant Transformation
por: Molognoni, Fernanda, et al.
Publicado: (2013)

Correction: Ras and Rac1, Frequently Mutated in Melanomas, Are Activated by Superoxide Anion, Modulate Dnmt1 Level and Are Causally Related to Melanocyte Malignant Transformation
por: Molognoni, Fernanda, et al.
Publicado: (2015)

Talimogene laherparepvec in combination with pembrolizumab leads to a complete response in a patient with refractory Merkel cell carcinoma
por: Lara, Kristi M., et al.
Publicado: (2018)

Gene co-expression and histone modification signatures are associated with melanoma progression, epithelial-to-mesenchymal transition, and metastasis
por: Azevedo, Hátylas, et al.
Publicado: (2020)

Apoptotic Cells Contribute to Melanoma Progression and This Effect is Partially Mediated by the Platelet-Activating Factor Receptor
por: Bachi, André Luis Lacerda, et al.
Publicado: (2012)

The Multi-Omic Landscape of Primary Breast Tumors and Their Metastases: Expanding the Efficacy of Actionable Therapeutic Targets
por: Yang, Guang, et al.
Publicado: (2022)

Mining Gene Expression Signature for the Detection of Pre-Malignant Melanocytes and Early Melanomas with Risk for Metastasis
por: de Souza, Camila Ferreira, et al.
Publicado: (2012)

Gene expression and promoter methylation of angiogenic and lymphangiogenic factors as prognostic markers in melanoma
por: Monteiro, Ana Carolina, et al.
Publicado: (2019)

Merkel Cell Polyomavirus DNA in Persons without Merkel Cell Carcinoma
por: Wieland, Ulrike, et al.
Publicado: (2009)

RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
por: Li, Hong-Tao, et al.
Publicado: (2023)

Genetic and Epigenetic Alterations in Bladder Cancer
por: Li, Hong-Tao, et al.
Publicado: (2016)

DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight
por: Weisenberger, Daniel J., et al.
Publicado: (2008)

A Multi-Omics Overview of Colorectal Cancer to Address Mechanisms of Disease, Metastasis, Patient Disparities and Outcomes
por: Yang, Guang, et al.
Publicado: (2023)

Detection of Merkel Cell Polyomavirus (MCPyV) DNA and Transcripts in Merkel Cell Carcinoma (MCC)
por: Passerini, Sara, et al.
Publicado: (2023)

Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy
por: Khuc, Emily, et al.
Publicado: (2017)

Improving needle biopsy accuracy in small renal mass using tumor-specific DNA methylation markers
por: Chopra, Sameer, et al.
Publicado: (2016)

DNA methylation enables transposable element-driven genome expansion
por: Zhou, Wanding, et al.
Publicado: (2020)

Merkel Cell Polyomavirus and Merkel Cell Carcinoma
por: Pietropaolo, Valeria, et al.
Publicado: (2020)

DETECTing Merkel Cell Polyomavirus in Merkel Tumors
por: Arora, Reety, et al.
Publicado: (2020)

Characterization of the Merkel Cell Carcinoma miRNome
por: Ning, Matthew S., et al.
Publicado: (2014)

Characterization of a Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma Cell Line CVG-1
por: Velásquez, Celestino, et al.
Publicado: (2018)

Merkel Cell Polyomavirus and Merkel Cell Carcinoma, France
por: Foulongne, Vincent, et al.
Publicado: (2008)

Merkel cell polyomavirus and cutaneous Merkel cell carcinoma
por: Minutilli, Ettore, et al.
Publicado: (2016)

Merkel cell polyomavirus and associated Merkel cell carcinoma
por: Yang, June F., et al.
Publicado: (2021)

DNA-methylation patterns imply a common cellular origin of virus- and UV-associated Merkel cell carcinoma
por: Gravemeyer, Jan, et al.
Publicado: (2021)

Identifying aggressive prostate cancer foci using a DNA methylation classifier
por: Mundbjerg, Kamilla, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_l5piq5cub2gppkhqr3asp64hdu