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Two randomized, double-blind, placebo-controlled trials and one open-label, long-term trial of brexpiprazole for the acute treatment of bipolar mania
BACKGROUND: Brexpiprazole is a dopamine/serotonin receptor partial agonist (D(2), 5-HT(1A)) and antagonist (5-HT(2A)) approved for treatment of schizophrenia and major depressive disorder (adjunct to antidepressants). AIMS: This study aimed to investigate brexpiprazole as monotherapy in acute mania...
Autores principales: | Vieta, Eduard, Sachs, Gary, Chang, Denise, Hellsten, Johan, Brewer, Claudette, Peters-Strickland, Timothy, Hefting, Nanco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366183/ https://www.ncbi.nlm.nih.gov/pubmed/33691517 http://dx.doi.org/10.1177/0269881120985102 |
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