MicroRNA‐199a‐5p aggravates angiotensin II–induced vascular smooth muscle cell senescence by targeting Sirtuin‐1 in abdominal aortic aneurysm

Vascular smooth muscle cells (VSMCs) senescence contributes to abdominal aortic aneurysm (AAA) formation although the underlying mechanisms remain unclear. This study aimed to investigate the role of miR‐199a‐5p in regulating VSMC senescence in AAA. VSMC senescence was determined by a senescence‐ass...

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Detalles Bibliográficos
Autores principales: Tao, Wuyuan, Hong, Yimei, He, Haiwei, Han, Qian, Mao, Mengmeng, Hu, Bei, Zhang, Hao, Huang, Xiaoran, You, Wei, Liang, Xiaoting, Zhang, Yuelin, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366448/
https://www.ncbi.nlm.nih.gov/pubmed/34132029
http://dx.doi.org/10.1111/jcmm.16485

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