HOTAIR lncRNA promotes epithelial–mesenchymal transition by redistributing LSD1 at regulatory chromatin regions

Epithelial‐to‐mesenchymal transition (EMT) describes the loss of epithelial traits and gain of mesenchymal traits by normal cells during development and by neoplastic cells during cancer metastasis. The long noncoding RNA HOTAIR triggers EMT, in part by serving as a scaffold for PRC2 and thus promot...

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Detalles Bibliográficos
Autores principales: Jarroux, Julien, Foretek, Dominika, Bertrand, Claire, Gabriel, Marc, Szachnowski, Ugo, Saci, Zohra, Guo, Shuling, Londoño‐Vallejo, Arturo, Pinskaya, Marina, Morillon, Antonin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366456/
https://www.ncbi.nlm.nih.gov/pubmed/33960111
http://dx.doi.org/10.15252/embr.202050193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366456/
https://www.ncbi.nlm.nih.gov/pubmed/33960111
http://dx.doi.org/10.15252/embr.202050193

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