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An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics

Next-generation multi-specific antibody therapeutics (MSATs) are engineered to combine several functional activities into one molecule to provide higher efficacy compared to conventional, mono-specific antibody therapeutics. However, highly engineered MSATs frequently display poor yields and less fa...

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Detalles Bibliográficos
Autores principales:	Furtmann, Norbert, Schneider, Marion, Spindler, Nadja, Steinmann, Bjoern, Li, Ziyu, Focken, Ingo, Meyer, Joachim, Dimova, Dilyana, Kroll, Katja, Leuschner, Wulf Dirk, Debeaumont, Audrey, Mathieu, Magali, Lange, Christian, Dittrich, Werner, Kruip, Jochen, Schmidt, Thorsten, Birkenfeld, Joerg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366542/ https://www.ncbi.nlm.nih.gov/pubmed/34382900 http://dx.doi.org/10.1080/19420862.2021.1955433

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