IFN-γ-induced ER stress impairs autophagy and triggers apoptosis in lung cancer cells

Interferon-gamma (IFN-γ) is a major effector molecule of immunity and a common feature of tumors responding to immunotherapy. Active IFN-γ signaling can directly trigger apoptosis and cell cycle arrest in human cancer cells. However, the mechanisms underlying these actions remain unclear. Here, we r...

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Detalles Bibliográficos
Autores principales: Fang, Can, Weng, Tao, Hu, Shaojie, Yuan, Zhiwei, Xiong, Hui, Huang, Bing, Cai, Yixin, Li, Lequn, Fu, Xiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366549/
https://www.ncbi.nlm.nih.gov/pubmed/34408924
http://dx.doi.org/10.1080/2162402X.2021.1962591

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