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Broad-spectrum in vitro antiviral activity of ODBG-P-RVn: an orally-available, lipid-modified monophosphate prodrug of remdesivir parent nucleoside (GS-441524)

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The intravenous administration of remdesivir for COVID-19 confines its utility to hospitalized patients. We evaluated the broad-spectrum antiviral activity of ODBG-P-RVn, an orally available, lipid-modified monophosphate prodrug of the remdesivir parent nucleoside (GS-441524) against viruses that ca...

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Detalles Bibliográficos
Autores principales:	Lo, Michael K., Shrivastava-Ranjan, Punya, Chatterjee, Payel, Flint, Mike, Beadle, James R., Valiaeva, Nadejda, Schooley, Robert T., Hostetler, Karl Y., Montgomery, Joel M., Spiropoulou, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366795/ https://www.ncbi.nlm.nih.gov/pubmed/34401879 http://dx.doi.org/10.1101/2021.08.06.455494

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