Antibody Attributes that Predict the Neutralization and Effector Function of Polyclonal Responses to SARS-CoV-2

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While antibodies provide significant protection from SARS-CoV-2 infection and disease sequelae, the specific attributes of the humoral response that contribute to immunity are incompletely defined. In this study, we employ machine learning to relate characteristics of the polyclonal antibody respons...

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Detalles Bibliográficos
Autores principales: Natarajan, Harini, Xu, Shiwei, Crowley, Andrew R., Butler, Savannah E., Weiner, Joshua A., Bloch, Evan M., Littlefield, Kirsten, Benner, Sarah E., Shrestha, Ruchee, Ajayi, Olivia, Wieland-Alter, Wendy, Sullivan, David, Shoham, Shmuel, Quinn, Thomas C., Casadevall, Arturo, Pekosz, Andrew, Redd, Andrew D., Tobian, Aaron A.R., Connor, Ruth I., Wright, Peter F., Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366811/
https://www.ncbi.nlm.nih.gov/pubmed/34401890
http://dx.doi.org/10.1101/2021.08.06.21261710
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