Cargando…

Novel test strategies for in vitro seizure liability assessment

INTRODUCTION: The increasing incidence of mental illnesses and neurodegenerative diseases results in a high demand for drugs targeting the central nervous system (CNS). These drugs easily reach the CNS, have a high affinity for CNS targets, and are prone to cause seizures as an adverse drug reaction...

Descripción completa

Detalles Bibliográficos
Autores principales: Tukker, Anke M., Westerink, Remco H. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367052/
https://www.ncbi.nlm.nih.gov/pubmed/33595380
http://dx.doi.org/10.1080/17425255.2021.1876026