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Novel test strategies for in vitro seizure liability assessment
INTRODUCTION: The increasing incidence of mental illnesses and neurodegenerative diseases results in a high demand for drugs targeting the central nervous system (CNS). These drugs easily reach the CNS, have a high affinity for CNS targets, and are prone to cause seizures as an adverse drug reaction...
Autores principales: | Tukker, Anke M., Westerink, Remco H. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367052/ https://www.ncbi.nlm.nih.gov/pubmed/33595380 http://dx.doi.org/10.1080/17425255.2021.1876026 |
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