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Progranulin Protects Against Airway Remodeling Through the Modulation of Autophagy via HMGB1 Suppression in House Dust Mite-Induced Chronic Asthma

PURPOSE: Airway remodeling is an important feature of chronic asthma, and yet there are few effective therapeutic strategies. Progranulin (PGRN) has been shown to have lung protective functions, but the role of PGRN in asthmatic airway remodeling is unclear. We aim to explore the protective potentia...

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Detalles Bibliográficos
Autores principales:	Liu, Meixuan, Shan, Mengtian, Zhang, Yunxuan, Guo, Zhongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367219/ https://www.ncbi.nlm.nih.gov/pubmed/34408470 http://dx.doi.org/10.2147/JIR.S322724

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