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A CTP-dependent gating mechanism enables ParB spreading on DNA

Proper chromosome segregation is essential in all living organisms. The ParA-ParB-parS system is widely employed for chromosome segregation in bacteria. Previously, we showed that Caulobacter crescentus ParB requires cytidine triphosphate to escape the nucleation site parS and spread by sliding to t...

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Detalles Bibliográficos
Autores principales: Jalal, Adam SB, Tran, Ngat T, Stevenson, Clare EM, Chimthanawala, Afroze, Badrinarayanan, Anjana, Lawson, David M, Le, Tung BK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367383/
https://www.ncbi.nlm.nih.gov/pubmed/34397383
http://dx.doi.org/10.7554/eLife.69676

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