Vitamin D suppresses bleomycin-induced pulmonary fibrosis by targeting the local renin–angiotensin system in the lung

Idiopathic pulmonary fibrosis (IPF) is a severe disorder leading to progressive and irreversible loss of pulmonary function. In this study we investigated the anti-fibrotic effect of vitamin D using a mouse model of IPF. Lung fibrosis was induced with bleomycin in vitamin D-sufficient and vitamin D-...

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Detalles Bibliográficos
Autores principales: Chang, Jianjun, Nie, Hongguang, Ge, Xin, Du, Jie, Liu, Weicheng, Li, Xue, Sun, Yue, Wei, Xinzhi, Xun, Zhe, Li, Yan Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367953/
https://www.ncbi.nlm.nih.gov/pubmed/34400742
http://dx.doi.org/10.1038/s41598-021-96152-7

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