Toll-like receptor-4 null mutation causes fetal loss and fetal growth restriction associated with impaired maternal immune tolerance in mice

Maternal immune adaptation to accommodate pregnancy depends on sufficient availability of regulatory T (Treg) cells to enable embryo implantation. Toll-like receptor 4 is implicated as a key upstream driver of a controlled inflammatory response, elicited by signals in male partner seminal fluid, to...

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Detalles Bibliográficos
Autores principales: Chan, Hon Y., Moldenhauer, Lachlan M., Groome, Holly M., Schjenken, John E., Robertson, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368181/
https://www.ncbi.nlm.nih.gov/pubmed/34400677
http://dx.doi.org/10.1038/s41598-021-95213-1

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