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Rapid target validation in a Cas9-inducible hiPSC derived kidney model

Recent advances in induced pluripotent stem cells (iPSCs), genome editing technologies and 3D organoid model systems highlight opportunities to develop new in vitro human disease models to serve drug discovery programs. An ideal disease model would accurately recapitulate the relevant disease phenot...

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Detalles Bibliográficos
Autores principales:	Shamshirgaran, Yasaman, Jonebring, Anna, Svensson, Anna, Leefa, Isabelle, Bohlooly-Y, Mohammad, Firth, Mike, Woollard, Kevin J., Hofherr, Alexis, Rogers, Ian M., Hicks, Ryan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368200/ https://www.ncbi.nlm.nih.gov/pubmed/34400685 http://dx.doi.org/10.1038/s41598-021-95986-5

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