Granzyme A Produced by γ(9)δ(2) T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity

Mycobacterium tuberculosis (Mtb), the pathological agent that causes tuberculosis (TB) is the number one infectious killer worldwide with one fourth of the world’s population currently infected. Data indicate that γ(9)δ(2) T cells secrete Granzyme A (GzmA) in the extracellular space triggering the i...

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Detalles Bibliográficos
Autores principales: Rasi, Valerio, Wood, David C., Eickhoff, Christopher S., Xia, Mei, Pozzi, Nicola, Edwards, Rachel L., Walch, Michael, Bovenschen, Niels, Hoft, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368726/
https://www.ncbi.nlm.nih.gov/pubmed/34413857
http://dx.doi.org/10.3389/fimmu.2021.712678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368726/
https://www.ncbi.nlm.nih.gov/pubmed/34413857
http://dx.doi.org/10.3389/fimmu.2021.712678

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