The epigenetic role of HTR1A antagonist in facilitaing GnRH expression for pubertal initiation control

Serotonin (5-hydroxytryptamine [5-HT]), a metabolite of tryptophan, acts on the components of the hypothalamus-hypophysis-gonad axis and induces puberty delay in mammals via 5-HT receptor 1A (HTR1A). However, the roles of HTR1A in the hypothalamus in pubertal regulation of gene expression are not fu...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Shasha, Shen, Yihang, Zang, Shaolian, Yin, Xiaoqin, Li, Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368778/
https://www.ncbi.nlm.nih.gov/pubmed/34458005
http://dx.doi.org/10.1016/j.omtn.2021.05.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368778/
https://www.ncbi.nlm.nih.gov/pubmed/34458005
http://dx.doi.org/10.1016/j.omtn.2021.05.014

Ejemplares similares