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The epigenetic role of HTR1A antagonist in facilitaing GnRH expression for pubertal initiation control

Serotonin (5-hydroxytryptamine [5-HT]), a metabolite of tryptophan, acts on the components of the hypothalamus-hypophysis-gonad axis and induces puberty delay in mammals via 5-HT receptor 1A (HTR1A). However, the roles of HTR1A in the hypothalamus in pubertal regulation of gene expression are not fu...

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Detalles Bibliográficos
Autores principales:	Zhou, Shasha, Shen, Yihang, Zang, Shaolian, Yin, Xiaoqin, Li, Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368778/ https://www.ncbi.nlm.nih.gov/pubmed/34458005 http://dx.doi.org/10.1016/j.omtn.2021.05.014

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