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Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population

INTRODUCTION: Donor liver graft quality plays an especially important role that contributes to the success of organ transplantation. Almost all local and international authors are interested in the techniques and results of transplantation, however, in Vietnam, there have not been any studies that r...

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Autores principales: Nguyen, Thanh Khiem, Trinh, Hong Son, Luong, Tuan Hiep, Ninh, Viet Khai, Pham, Gia Anh, Nguyen, Ham Hoi, Bui, Trung Nghia, Dang, Kim Khue, Hoang, Tuan, Nguyen, Quang Nghia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369000/
https://www.ncbi.nlm.nih.gov/pubmed/34429944
http://dx.doi.org/10.1016/j.amsu.2021.102654
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author Nguyen, Thanh Khiem
Trinh, Hong Son
Luong, Tuan Hiep
Ninh, Viet Khai
Pham, Gia Anh
Nguyen, Ham Hoi
Bui, Trung Nghia
Dang, Kim Khue
Hoang, Tuan
Nguyen, Quang Nghia
author_facet Nguyen, Thanh Khiem
Trinh, Hong Son
Luong, Tuan Hiep
Ninh, Viet Khai
Pham, Gia Anh
Nguyen, Ham Hoi
Bui, Trung Nghia
Dang, Kim Khue
Hoang, Tuan
Nguyen, Quang Nghia
author_sort Nguyen, Thanh Khiem
collection PubMed
description INTRODUCTION: Donor liver graft quality plays an especially important role that contributes to the success of organ transplantation. Almost all local and international authors are interested in the techniques and results of transplantation, however, in Vietnam, there have not been any studies that report the results of liver procurement from brain-dead donors from a technical perspective as well as the morphology and function of the transplanted organ. MATERIALS AND METHOD: This study is descriptive cross-section study with analysis of retrospective occurrences of a series of cases of liver procurement from brain-dead donors from March 2010 to March 2020. All cases were proceeded the multiple organ procurement with warm liver dissection and in vivo cannulation and perfusion. RESULTS: The average age of brain-dead donors was 29.7 ± 10.7 (18–69), 92.16% of the harvested organs were of good quality macroscopically; and the rate of anatomical modification was 33.3% that occurred mostly in the left hepatic artery (LHA). Technically, warm dissection was proceeded in majority of cases (98,0%), the graft implantation was performed by this technique with mean cold ischemia time (CIT) of 190,0 ± 100,5 min and WIT of 74,0 ± 39,2 s. There were no complications relating to graft injuries occurring during procurement and no primary liver failure, good results accounted for 94.1% of the total number of transplants postoperatively. CONCLUSION: Multiple organ procurement with warm liver dissection and in vivo cannulation and perfusion was a safe technique and may be effective by avoiding any donor's damages in cold-phase dissection.
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spelling pubmed-83690002021-08-23 Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population Nguyen, Thanh Khiem Trinh, Hong Son Luong, Tuan Hiep Ninh, Viet Khai Pham, Gia Anh Nguyen, Ham Hoi Bui, Trung Nghia Dang, Kim Khue Hoang, Tuan Nguyen, Quang Nghia Ann Med Surg (Lond) Case Series INTRODUCTION: Donor liver graft quality plays an especially important role that contributes to the success of organ transplantation. Almost all local and international authors are interested in the techniques and results of transplantation, however, in Vietnam, there have not been any studies that report the results of liver procurement from brain-dead donors from a technical perspective as well as the morphology and function of the transplanted organ. MATERIALS AND METHOD: This study is descriptive cross-section study with analysis of retrospective occurrences of a series of cases of liver procurement from brain-dead donors from March 2010 to March 2020. All cases were proceeded the multiple organ procurement with warm liver dissection and in vivo cannulation and perfusion. RESULTS: The average age of brain-dead donors was 29.7 ± 10.7 (18–69), 92.16% of the harvested organs were of good quality macroscopically; and the rate of anatomical modification was 33.3% that occurred mostly in the left hepatic artery (LHA). Technically, warm dissection was proceeded in majority of cases (98,0%), the graft implantation was performed by this technique with mean cold ischemia time (CIT) of 190,0 ± 100,5 min and WIT of 74,0 ± 39,2 s. There were no complications relating to graft injuries occurring during procurement and no primary liver failure, good results accounted for 94.1% of the total number of transplants postoperatively. CONCLUSION: Multiple organ procurement with warm liver dissection and in vivo cannulation and perfusion was a safe technique and may be effective by avoiding any donor's damages in cold-phase dissection. Elsevier 2021-07-31 /pmc/articles/PMC8369000/ /pubmed/34429944 http://dx.doi.org/10.1016/j.amsu.2021.102654 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Series
Nguyen, Thanh Khiem
Trinh, Hong Son
Luong, Tuan Hiep
Ninh, Viet Khai
Pham, Gia Anh
Nguyen, Ham Hoi
Bui, Trung Nghia
Dang, Kim Khue
Hoang, Tuan
Nguyen, Quang Nghia
Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population
title Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population
title_full Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population
title_fullStr Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population
title_full_unstemmed Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population
title_short Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population
title_sort technical characteristics and quality of grafts in liver procurement from brain-dead donors: a single-center study in vietnamese population
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369000/
https://www.ncbi.nlm.nih.gov/pubmed/34429944
http://dx.doi.org/10.1016/j.amsu.2021.102654
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