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Interaction of Hepatitis B Virus X Protein with the Pregnane X Receptor Enhances the Synergistic Effects of Aflatoxin B1 and Hepatitis B Virus on Promoting Hepatocarcinogenesis

BACKGROUND AND AIMS: Hepatitis B virus (HBV) infection has been found to increase hepatocellular sensitivity to carcinogenic xenobiotics, by unknown mechanisms, in the generation of hepatocellular carcinoma. The pregnane X receptor (PXR) is a key regulator of the body’s defense against xenobiotics,...

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Detalles Bibliográficos
Autores principales:	Niu, Yongdong, Fan, Shaohua, Luo, Qin, Chen, Liming, Huang, Danmei, Chang, Wenjun, Qin, Wenxin, Shi, Ganggang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	XIA & HE Publishing Inc. 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369009/ https://www.ncbi.nlm.nih.gov/pubmed/34447675 http://dx.doi.org/10.14218/JCTH.2021.00036

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