Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus

In the central nervous system, developmental and pathophysiologic conditions cause a large-scale reorganization of functional connectivity of neural circuits. Here, by using a mouse model for peripheral sensory nerve injury, we present a protocol for combined electrophysiological and anatomical tech...

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Detalles Bibliográficos
Autores principales: Ueta, Yoshifumi, Miyata, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369072/
https://www.ncbi.nlm.nih.gov/pubmed/34430916
http://dx.doi.org/10.1016/j.xpro.2021.100743
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author Ueta, Yoshifumi
Miyata, Mariko
author_facet Ueta, Yoshifumi
Miyata, Mariko
author_sort Ueta, Yoshifumi
collection PubMed
description In the central nervous system, developmental and pathophysiologic conditions cause a large-scale reorganization of functional connectivity of neural circuits. Here, by using a mouse model for peripheral sensory nerve injury, we present a protocol for combined electrophysiological and anatomical techniques to identify neural basis of synaptic remodeling in the mouse whisker thalamus. Our protocol provides comprehensive approaches to analyze both structural and functional components of synaptic remodeling. For complete details on the use and execution of this protocol, please refer to Ueta and Miyata, (2021).
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spelling pubmed-83690722021-08-23 Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus Ueta, Yoshifumi Miyata, Mariko STAR Protoc Protocol In the central nervous system, developmental and pathophysiologic conditions cause a large-scale reorganization of functional connectivity of neural circuits. Here, by using a mouse model for peripheral sensory nerve injury, we present a protocol for combined electrophysiological and anatomical techniques to identify neural basis of synaptic remodeling in the mouse whisker thalamus. Our protocol provides comprehensive approaches to analyze both structural and functional components of synaptic remodeling. For complete details on the use and execution of this protocol, please refer to Ueta and Miyata, (2021). Elsevier 2021-08-13 /pmc/articles/PMC8369072/ /pubmed/34430916 http://dx.doi.org/10.1016/j.xpro.2021.100743 Text en © 2021. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Protocol
Ueta, Yoshifumi
Miyata, Mariko
Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
title Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
title_full Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
title_fullStr Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
title_full_unstemmed Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
title_short Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
title_sort electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369072/
https://www.ncbi.nlm.nih.gov/pubmed/34430916
http://dx.doi.org/10.1016/j.xpro.2021.100743
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AT miyatamariko electrophysiologicalandanatomicalcharacterizationofsynapticremodelinginthemousewhiskerthalamus

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