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DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice

Despite remarkable scientific advances in the understanding of molecular mechanisms for sepsis, therapeutic options are far from satisfactory. High mobility group box 1 (HMGB1), one of the ligands of receptor for advanced glycation end products (RAGE), is a late mediator of lethality in septic mice....

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Detalles Bibliográficos
Autores principales:	Koga, Yoshinori, Sotokawauchi, Ami, Higashimoto, Yuichiro, Nishino, Yuri, Hashizume, Naoki, Kakuma, Tatsuyuki, Akiba, Jun, Tanaka, Yoshiaki, Matsui, Takanori, Yagi, Minoru, Yamagishi, Sho-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369179/ https://www.ncbi.nlm.nih.gov/pubmed/34413930 http://dx.doi.org/10.1155/2021/9932311

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