Cargando…

GINS1 Induced Sorafenib Resistance by Promoting Cancer Stem Properties in Human Hepatocellular Cancer Cells

Hepatocellular carcinoma (HCC) is characterized by a high rate of incidence and recurrence, and resistance to chemotherapy may aggravate the poor prognosis of HCC patients. Sorafenib resistance is a conundrum to the treatment of advanced/recurrent HCC. Therefore, studies on the molecular pathogenesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Sheng, Wu, Lina, Zhang, Hong, Liu, Xijuan, Wang, Zilei, Dong, Bin, Cao, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369484/ https://www.ncbi.nlm.nih.gov/pubmed/34414190 http://dx.doi.org/10.3389/fcell.2021.711894

Ejemplares similares

Tissue-Specific Requirement for the GINS Complex During Zebrafish Development
por: Varga, Máté, et al.
Publicado: (2020)

Comprehensive analysis of GINS subunits prognostic value and ceRNA network in sarcoma
por: Zhou, Chuqiao, et al.
Publicado: (2022)

Promoter Hypomethylation and miR-145-5p Downregulation- Mediated HDAC11 Overexpression Promotes Sorafenib Resistance and Metastasis of Hepatocellular Carcinoma Cells
por: Wang, Wenlong, et al.
Publicado: (2020)

A comprehensive review of the relationship between autophagy and sorafenib-resistance in hepatocellular carcinoma: ferroptosis is noteworthy
por: Zhang, Kangnan, et al.
Publicado: (2023)

LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells
por: Chen, Lingxi, et al.
Publicado: (2021)

Emerging Regulatory Mechanisms Involved in Liver Cancer Stem Cell Properties in Hepatocellular Carcinoma
por: Lv, Duoduo, et al.
Publicado: (2021)

M(6)A-Mediated Upregulation of LINC00106 Promotes Stemness and Metastasis Properties of Hepatocellular Carcinoma via Sponging Let7f
por: Liang, Wenjin, et al.
Publicado: (2021)

Dysregulated MicroRNA Fingerprints and Methylation Patterns in Hepatocellular Carcinoma, Cancer Stem Cells, and Mesenchymal Stem Cells
por: Nasr, Mohamed A., et al.
Publicado: (2019)

Metformin Resensitizes Sorafenib-Resistant HCC Cells Through AMPK-Dependent Autophagy Activation
por: Lai, Hong-Yue, et al.
Publicado: (2021)

Immunological Value of Prognostic Signature Based on Cancer Stem Cell Characteristics in Hepatocellular Carcinoma
por: Xu, Qianhui, et al.
Publicado: (2021)

Novel Paired Cell Lines for the Study of Lipid Metabolism and Cancer Stemness of Hepatocellular Carcinoma
por: Cheng, Yun-Hsin, et al.
Publicado: (2022)

Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway
por: Cao, Wanshuang, et al.
Publicado: (2021)

Editorial: Novel therapeutic approaches for biliary tract cancer and hepatocellular carcinoma
por: Bekric, Dino, et al.
Publicado: (2023)

Regulation of Formation, Stemness and Therapeutic Resistance of Cancer Stem Cells
por: Jing, Nan, et al.
Publicado: (2021)

DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7
por: De Jesús-Kim, Lorraine, et al.
Publicado: (2021)

Identification and validation of potential key long noncoding RNAs in sorafenib-resistant hepatocellular carcinoma cells
por: Wu, Manya, et al.
Publicado: (2020)

ARPC2: A Pan-Cancer Prognostic and Immunological Biomarker That Promotes Hepatocellular Carcinoma Cell Proliferation and Invasion
por: Huang, Shenglan, et al.
Publicado: (2022)

Exosomal Long Non-coding RNA HOTTIP Increases Resistance of Colorectal Cancer Cells to Mitomycin via Impairing MiR-214-Mediated Degradation of KPNA3
por: Chen, Xijuan, et al.
Publicado: (2021)

Cancer-Associated Fibroblasts Promote Vascular Invasion of Hepatocellular Carcinoma via Downregulating Decorin-integrin β1 Signaling
por: Zheng, Xiaobo, et al.
Publicado: (2021)

Hypermethylation and Downregulation of UTP6 Are Associated With Stemness Properties, Chemoradiotherapy Resistance, and Prognosis in Rectal Cancer: A Co-expression Network Analysis
por: Zhang, Yiyi, et al.
Publicado: (2021)

Tumor-Educated Neutrophils Activate Mesenchymal Stem Cells to Promote Gastric Cancer Growth and Metastasis
por: Zhang, Jiahui, et al.
Publicado: (2020)

Mesenchymal Stem/Stromal Cells in Progressive Fibrogenic Involvement and Anti-Fibrosis Therapeutic Properties
por: Li, Chenghai, et al.
Publicado: (2022)

Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling
por: Ji, Zhaodong, et al.
Publicado: (2021)

Detachment Activated CyPA/CD147 Induces Cancer Stem Cell Potential in Non-stem Breast Cancer Cells
por: Meng, Yao, et al.
Publicado: (2020)

Sulfatase 2-Induced Cancer-Associated Fibroblasts Promote Hepatocellular Carcinoma Progression via Inhibition of Apoptosis and Induction of Epithelial-to-Mesenchymal Transition
por: Wang, Cong, et al.
Publicado: (2021)

Breast Cancer Stem Cell-Derived ANXA6-Containing Exosomes Sustain Paclitaxel Resistance and Cancer Aggressiveness in Breast Cancer
por: Guo, Zihe, et al.
Publicado: (2021)

SNORA72 Activates the Notch1/c-Myc Pathway to Promote Stemness Transformation of Ovarian Cancer Cells
por: Zhang, Liwen, et al.
Publicado: (2020)

Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutations
por: Tornesello, Maria Lina, et al.
Publicado: (2023)

Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1
por: Teo, Wee S., et al.
Publicado: (2020)

Probing Synergistic Targets by Natural Compounds for Hepatocellular Carcinoma
por: Gao, Jian, et al.
Publicado: (2021)

Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α
por: Wang, Meng, et al.
Publicado: (2021)

6-Phosphogluconolactonase Promotes Hepatocellular Carcinogenesis by Activating Pentose Phosphate Pathway
por: Li, Changzheng, et al.
Publicado: (2021)

Corrigendum: SNORA72 activates the Notch1/c-Myc pathway to promote stemness transformation of ovarian cancer cells
por: Zhang, Liwen, et al.
Publicado: (2022)

The Role of the Extracellular Matrix in Cancer Stemness
por: Nallanthighal, Sameera, et al.
Publicado: (2019)

Hsa_Circ_0001860 Promotes Smad7 to Enhance MPA Resistance in Endometrial Cancer via miR-520h
por: Yuan, Shuang, et al.
Publicado: (2021)

Cancer Stem Cells: Emerging Key Players in Immune Evasion of Cancers
por: Lei, Martina Mang Leng, et al.
Publicado: (2021)

Targeting Autophagy in Thyroid Cancer: EMT, Apoptosis, and Cancer Stem Cells
por: Holm, Tammy M., et al.
Publicado: (2022)

Profiling and targeting cancer stem cell signaling pathways for cancer therapeutics
por: Borlongan, Mia C., et al.
Publicado: (2023)

miR-92a-3p Promoted EMT via Targeting LATS1 in Cervical Cancer Stem Cells
por: Liu, Shuangyue, et al.
Publicado: (2021)

RPL19 Is a Prognostic Biomarker and Promotes Tumor Progression in Hepatocellular Carcinoma
por: Rao, Benchen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q6lbgdj3apc6tdhnir9de71e69