Combining Cell Envelope Stress Reporter Assays in a Screening Approach to Identify BAM Complex Inhibitors

[Image: see text] The development of new antibiotics is particularly problematic in Gram-negative bacteria due to the presence of the outer membrane (OM), which serves as a permeability barrier. Recently, the β-barrel assembly machine (BAM), located in the OM and responsible for β-barrel type OM pro...

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Detalles Bibliográficos
Autores principales: Steenhuis, Maurice, Corona, Federico, ten Hagen-Jongman, Corinne M., Vollmer, Waldemar, Lambin, Dominique, Selhorst, Philippe, Klaassen, Hugo, Versele, Matthias, Chaltin, Patrick, Luirink, Joen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369490/
https://www.ncbi.nlm.nih.gov/pubmed/34125508
http://dx.doi.org/10.1021/acsinfecdis.0c00728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369490/
https://www.ncbi.nlm.nih.gov/pubmed/34125508
http://dx.doi.org/10.1021/acsinfecdis.0c00728

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