Cargando…
Combining Cell Envelope Stress Reporter Assays in a Screening Approach to Identify BAM Complex Inhibitors
[Image: see text] The development of new antibiotics is particularly problematic in Gram-negative bacteria due to the presence of the outer membrane (OM), which serves as a permeability barrier. Recently, the β-barrel assembly machine (BAM), located in the OM and responsible for β-barrel type OM pro...
Autores principales: | Steenhuis, Maurice, Corona, Federico, ten Hagen-Jongman, Corinne M., Vollmer, Waldemar, Lambin, Dominique, Selhorst, Philippe, Klaassen, Hugo, Versele, Matthias, Chaltin, Patrick, Luirink, Joen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369490/ https://www.ncbi.nlm.nih.gov/pubmed/34125508 http://dx.doi.org/10.1021/acsinfecdis.0c00728 |
Ejemplares similares
-
Stress-Based High-Throughput Screening Assays to Identify Inhibitors of Cell Envelope Biogenesis
por: Steenhuis, Maurice, et al.
Publicado: (2020) -
The Escherichia coli Outer Membrane β-Barrel Assembly Machinery (BAM) Crosstalks with the Divisome
por: Consoli, Elisa, et al.
Publicado: (2021) -
Comparing autotransporter β-domain configurations for their capacity to secrete heterologous proteins to the cell surface
por: Jong, Wouter S. P., et al.
Publicado: (2018) -
Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras
por: Phan, Trang H., et al.
Publicado: (2021) -
Overexpression of the Bam Complex Improves the Production of Chlamydia trachomatis MOMP in the E. coli Outer Membrane
por: Huynh, Dung T., et al.
Publicado: (2022)