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Quantifying the phase separation property of chromatin-associated proteins under physiological conditions using an anti-1,6-hexanediol index

BACKGROUND: Liquid-liquid phase separation (LLPS) is an important organizing principle for biomolecular condensation and chromosome compartmentalization. However, while many proteins have been reported to undergo LLPS, quantitative and global analysis of chromatin LLPS property remains absent. RESUL...

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Detalles Bibliográficos
Autores principales:	Shi, Minglei, You, Kaiqiang, Chen, Taoyu, Hou, Chao, Liang, Zhengyu, Liu, Mingwei, Wang, Jifeng, Wei, Taotao, Qin, Jun, Chen, Yang, Zhang, Michael Q., Li, Tingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369651/ https://www.ncbi.nlm.nih.gov/pubmed/34404448 http://dx.doi.org/10.1186/s13059-021-02456-2

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